Losing weight can be challenging, especially when traditional methods like diet and exercise don’t provide the desired results. For many, GLP-1 medications are the light at the end of a very dark tunnel in their struggle with excess pounds. These medications work by regulating hunger and promoting fat loss in a safe, medically supervised manner. In this blog, Dr. Brook Seeley explores the effectiveness, potential side effects, and benefits of using GLP-1 receptor agonists for reducing weight.
What Is GLP1 and How Does It Work?
Many of our patients wonder: “How does GLP-1 work for weight loss?” GLP-1 is a hormone naturally produced by the body. Initially developed for managing type 2 diabetes, medications that mimic GLP-1 help regulate blood sugar levels by stimulating insulin secretion and inhibiting glucagon release. Their appetite-regulating effects were quickly noted to be a secondary benefit, leading to their rising popularity as weight loss aids. When used as a medication, GLP-1 receptor agonists like semaglutide, the active ingredient in Wegovy® and Ozempic®, mimic this hormone, helping patients feel fuller for longer and making it easier to maintain a healthier low-calorie diet without feeling deprived.
Effectiveness of GLP-1 Receptor Agonists for Weight Loss
When used as part of a comprehensive weight management program, GLP-1 medications are extremely safe and effective. Studies show that patients using GLP-1 medications can experience significant weight loss, routinely losing 15-25% of their body weight, especially when combined with healthy eating and exercise. It is a medically-backed solution that can help kickstart the weight loss journey for many who are at their wit’s end with conventional weight loss methods.
Which GLP-1 Medication Is Best for Weight Loss?
When considering GLP-1 agonists for weight loss, it’s essential to explore the multiple options available through Dr. Seeley’s weight management program here at Connecticut Facial Plastic Surgery. These include semaglutide and tirzepatide, the active ingredients found in medications such as Ozempic®, Wegovy®, Zepbound®, and Mounjaro®. The right choice depends on the individual’s health needs and weight loss goals.
Wegovy®
Wegovy® (semaglutide) is specifically indicated for weight loss. By mimicking GLP-1, a hormone that regulates appetite, it helps patients feel full longer and thus they consume fewer calories. Typically prescribed for long-term use, Wegovy® is effective in promoting significant weight loss when paired with a healthy diet and exercise regimen. Studies suggest an average weight loss of about 15% of the original body weight, although individuals may lose more or less.
Ozempic®
Ozempic® (semaglutide) is another GLP-1 agonist, and although it has the same active ingredient and is made by the same company, it is specifically indicated for the treatment of diabetes. While it was originally developed for diabetes management, it has proven to be effective in reducing body weight by curbing appetite and slowing digestion, and this has made it extremely popular and thus expensive and hard to get. Ozempic® can certainly be integrated into a medically supervised weight loss plan, ensuring safe and effective weight management.
Zepbound®
Zepbound® (tirzepatide) is a newer GLP-1 receptor agonist that not only helps with weight management but also supports metabolic health. In addition to being a GLP-1 medication, it has a second component known as GIP, or gastric inhibitory polypeptide. This combination drug is touted as increasing the degree of weight loss to an average of up to 25%, and it has the added benefits of potentially having fewer side effects and better preservation of muscle mass. By influencing appetite regulation and enhancing satiety, Zepbound® can aid individuals in achieving their weight loss goals while promoting overall well-being. It’s essential to discuss your personal situation with Dr. Seeley’s team in Farmington or Wethersfield to determine if Zepbound® is the right choice for your weight management needs.
Mounjaro®
Mounjaro® (tirzepatide) also offers a unique approach to weight management by acting on multiple receptors, helping regulate both appetite and glucose levels. While similar to Zepbound®, it is specifically indicated for diabetes management. Its dual action can make Mounjaro® particularly effective for individuals looking to lose weight while also addressing other metabolic concerns. Consulting with Dr. Seeley can help you understand how Mounjaro® fits into your weight loss strategy.
Semaglutide and Tirzepatide
Due to the international demand for the branded medications described above, compounded semaglutide and tirzepatide have become available and extremely popular. Through our relationship with Dr. Well and Build My Health, we have been able to obtain these high-quality medications that are extremely pure, safe, and effective, and this allows us to provide our patients with the medications they need to develop a maintainable and effective weight loss program at a fraction of the cost of the branded medications which are frequently unobtainable.
Medical Supervision Is Key to Reducing Potential Side Effects
While GLP-1 agonists are effective for weight loss and are generally considered safe, some individuals may experience side effects, especially during the early stages of treatment and if they recently increased their dosage. These side effects tend to be mild and often subside as the body adapts to the GLP-1 dosage for weight loss. It is essential to work with a healthcare provider like Dr. Seeley, who monitors progress and adjusts the treatment plan as needed to minimize discomfort and ensure patient safety. Here are some common and less common side effects:
- Nausea
- Diarrhea
- Constipation
- Abdominal pain
- Vomiting
- Indigestion
- Fatigue
- Dizziness
- Headache
In rare cases, more serious side effects can occur, such as pancreatitis and sarcopenia. Some people are not able to take these medications, including those who are pregnant, have a known eating disorder, or have personal or family histories of medullary thyroid cancer or MEN2 syndrome. This is why it’s crucial to use GLP-1 medications for weight loss under close medical supervision to manage risks and side effects effectively.
Take Control of Your GLP-1 Weight Loss Journey
If you’ve been struggling to lose weight and need a safe, medically supervised approach, GLP-1 medications might be the solution you’re looking for. These treatments, especially when combined with healthy lifestyle changes, ongoing support, and motivation, offer an effective way to achieve your goals.
Start your Aesthetic Journey Today!
Ready to schedule a consultation with one of our board-certified plastic surgeons? Click the link below to fill out your information and start for the next steps towards a new you!